Ultimate Nucleotide

Nucleotides supports Optimally functioning immune system

There are many reasons why taking a nucleotide supplement benefits your health.

Nucleotides are the basic building blocks of all the DNA and RNA in your body, they are the ‘letters’ in which the genetic information is written. As such they are fundamental to life. Every time cells in your body divide they need to use up nucleotides to create new DNA and new chromosomes. One of the benefits of taking supplemental nucleotides is to allow you to resist infections better.

One of the-best characterized action of nucleotides, is their support of an optimally functioning immune system.

Our bodies are constantly under attack from pathogenic bacteria and viruses. The immune system is the reason we can withstand the vast majority of the attacks and only fall ill occasionally. If our immune systems don’t work at optimal efficiency we become prone to frequent colds, more susceptible to flu viruses, and increase the risk of catching a more serious illness. Like all the other systems in the body, our immune system requires the correct nutrients, and there is a wealth of scientific evidence that points to the fact that supplemental nucleotides act to boost the immune system.

Nucleotides, specifically adenosine triphosphate (ATP) and guanine triphosphate (GTP) have additional functions, beyond being used to make nucleic acid chains.

They can be converted into signaling molecules like cyclic AMP (cAMP), which act as second messengers, mediating the actions of first messengers like hormones or cytokines, which act outside cells to intracellular actions, which frequently result in upregulating the expression of specific genes. By ensuring an optimal level of the second messengers, nucleotide supplements create the environment for optimal signal transduction and allow the immune system to be modulated to meet the challenges it is faced with on a daily basis.

Nucleotides are also necessary for the production of interleukin-2 (IL2), a powerful cytokine produced by helper T-cells, which stimulates their proliferation when they encounter bacteria, viruses or other pathogens.

Nucleotide deprived diets reduce the production of interleukin-2. Nucleotides are therefore necessary for correct maturation and function of helper T-cells. On the other hand, helper T-cells are essential for the proper functioning of the whole immune system.